In this fascinating panel from The Amazing Spider-Man #88 (1970), readers learn that longtime Daily Bugle secretary (and former girlfriend of Peter Parker) Betty Brant is telepathic! As indicated by the puffy cloud shape of his word balloon, Peter is merely thinking about J. Jonah Jameson's whereabouts, but Betty speaks aloud in answer to Peter's unspoken musings. Betty is clearly a mutant - she should seek out the help of Professor X and join the X-Men!
I suppose it's also possible that Betty merely intuited Peter's thoughts. Or that the artist simply used the wrong form of word balloon.